Nadim · Golowasch · Bucher

Welcome to the STG lab!

Our laboratory is part of the Federated Department of Biological Sciences of the New Jersey Institute of Technology (NJIT) and Rutgers University Newark. It is run by three Principal Investigators, Farzan Nadim, Jorge Golowasch, and Dirk Bucher, all faculty in the department. We use both experimental and theoretical approaches to study the neurophysiology of a small central pattern generating circuit in lobsters and crabs, the stomatogastric ganglion (STG). Central pattern generators (CPGs) are networks of nerve cells in the central nervous system that generate the basic patterned electrical activity underlying most rhythmic behaviors like walking and breathing in all animals. We are taking advantage of the experimental accessibility of the crustacean nervous system to uncover fundamental principles that govern neural processing across all animal and human nervous systems.

  • STG neurons3D reconstructions of confocal images
  • Central Pattern GenerationThe pyloric circuit and the rhythm it produces
  • Decapod CrustaceansJonah crab and Maine lobster, our experimental animals
  • Neuropil structure of the STGCrab (l, m) and lobster (r) STGs. Stained synaptic contacts are shown in red.
1 2 3 4
bootstrap carousel by v5.6


The Lab moved to the NJIT campus!

We left Boyden Hall on the Rutgers campus and moved across the street to the newly renovated 4th floor of the Central King Building on the NJIT campus, with more space and completly new furnishings!

New Lab Members

Lihong Hao, Ph.D. joined the lab as a postdoctoral fellow. Lihong received her Ph.D. in Physiology at Rutgers University Medical School for work on glucose-sensing neurons. She is interested in cellular biophysics and will be working on functional implications of ionic current co-regulation.

Herve Nganguia, Ph.D. joined the lab as a postdoctoral fellow. Herve received his Ph.D. in Mathematics at NJIT for work on fluid dynamics. He is interested in computational neuroscience and will be working on the theoretical implications of axonal neuromodulation for neural coding.

Xinping (Lily) Li joined the lab as a graduate student. Lily received her undergraduate degree from Hongkong Baptist University and joined the Biology Ph.D. Program in 2013. She is interested in both experimental and theoretical neurophysiology and will study neuropeptide modulation of circuit dynamics.

Latest Papers

Veronica Garcia, Nelly Daur, and Dirk Bucher, together with the Schulz lab at Mizzou, published a paper on cell-type specific neuropeptide receptor expression in The Journal of Neuroscience:

Garcia VJ, Daur N, Temporal S, Schulz DJ, and Bucher D (2015) Neuropeptide receptor transcript expression levels and magnitude of ionic current responses show cell type-specific differences in a small motor circuit. J Neurosci 35:6786-6800.   PubMed  

Hua-an Tseng, Diana Martinez, and Farzan Nadim published a paper on the implications of resonance properties for network function in The Journal of Neuroscience:

Tseng HA, Martinez D, Nadim F (2014) The frequency preference of neurons and synapses in a recurrent oscillatory network. J Neurosci 34:12933-45.   PubMed  

Farzan Nadim and Dirk Bucher published a review on neuromodulation for an upcoming special issue in Current Opinion in Neurobiology:

Nadim F, Bucher D (2014) Neuromodulation of neurons and synapses. Curr Opin Neurobiol 29C:48-56.   PubMed  

Jorge Golowasch published a review on the regulation of neuronal excitability:

Golowasch J (2014) Ionic Current Variability and Functional Stability in the Nervous System. BioScience 64:570-580.   Journal